HPV Natural Treatment

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Gene-Eden-VIR/Novirin is a natural treatment, which was designed to help the immune system target the latent Human Papillomavirus (HPV). A post marketing clinical study showed that Gene-Eden-VIR/Novirin decreased symptoms of a HPV infection. A second post marketing clinical study showed that Gene-Eden-VIR/Novirin decreased the feeling of physical and mental fatigue associated with such infection. Both studies followed the FDA guidelines for clinical studies.

Both clinical studies were published in medical journal Pharmacology and Pharmacy. The first clinical study was published in the special edition on Advances in Antiviral Drugs.

The first study concluded: “… the clinical study showed that Gene-Eden-VIR is a safe and effective treatment against the Human Papillomavirus (HPV) (and other viruses). Therefore, health care practitioners should recommend Gene-Eden-VIR as a safe and effective antiviral treatment against these viruses.”

These studies provide a scientific proof that Gene-Eden-VIR/Novirin actually works. To quote from the first study, “this study showed that the natural product Gene-Eden-VIR/Novirin safely and effectively decreases symptoms in individuals infected with the HPV (and other viruses).”

Although both studies are written in a language suitable for scientists, you can read them or their abstracts on the home page. You can also watch Dr. Hanan Polansky, one of the scientists who conducted the study, explains it.

The following information was published by the Centers for Disease Control and Prevention (CDC) on its website. In brackets and italic letters, you can find our comments on the CDC information. Also note our yellow highlights.

What is genital HPV infection?

Genital Human Papillomavirus (HPV) is the most common sexually transmitted infection (STI). The virus infects the skin and mucous membranes. There are more than 40 HPV types that can infect the genital areas of men and women, including the skin of the penis, vulva (area outside the vagina), and anus, and the linings of the vagina, cervix, and rectum. You cannot see HPV. Most people who become infected with HPV do not even know they have it.

[The virus in these people is in a latent state.]

What are the symptoms and potential consequences of HPV?

Most people with HPV do not develop symptoms or health problems. But sometimes, certain types of HPV can cause genital warts in men and women. Other HPV types can cause cervical cancer and other less common cancers, such as cancers of the vulva, vagina, anus, and penis. The types of HPV that can cause genital warts are not the same as the types that can cause cancer.

[Dr. Hanan Polansky describes in his book how the latent Human Papillomavirus (HPV) can cause cancer. Click on Simple Explanation of Dr. Polansky’s Discovery, to read more.]

HPV types are often referred to as “low-risk” (wart-causing) or “high-risk” (cancer-causing), based on whether they put a person at risk for cancer. In 90% of cases, the body’s immune system clears the HPV infection naturally within two years. This is true of both high-risk and low-risk types.

[Note: In 10% of the cases the immune system is too weak to clear the latent HPV! In these cases, Gene-Eden-VIR/Novirin can help the immune system clear the latent HPV virus.]

Genital warts usually appear as small bumps or groups of bumps, usually in the genital area. They can be raised or flat, single or multiple, small or large, and sometimes cauliflower shaped. They can appear on the vulva, in or around the vagina or anus, on the cervix, and on the penis, scrotum, groin, or thigh. Warts may appear within weeks or months after sexual contact with an infected person. Or, they may not appear at all. If left untreated, genital warts may go away, remain unchanged, or increase in size or number. They will not turn into cancer.

Discreet and Confidential

Many people are infected with latent viruses. However, most of them don’t want others to know about it. An infection is a private matter, and most people would like their infection to remain confidential. To protect your privacy, we do the following:

1. Shipping: We will always ship your order in a plain discrete envelope. The envelope has no external packing list, and no indication of its content.

2. Label: The label on the bottle does not mention the words Herpes, HPV, or any other virus, or disease. If asked, you can easily and truthfully say that you take Gene-Eden-VIR to boost your immune system.

3. Personal information: We keep your records safe, and we will never share your personal information with anyone else (see details in our privacy policy). 

Cervical cancer does not have symptoms until it is quite advanced. For this reason, it is important for women to get screened regularly for cervical cancer.

[Screening is very important. However, if you are already infected with the HPV virus, Gene-Eden-VIR/Novirin can help your immune system target the latent human papillomavirus. Scientists at the Center for the Biology of Chronic Disease conducted a clinical study of Gene-Eden-VIR/Novirin. The clinical study showed that Gene-Eden-VIR/Novirin is safe and effective. The study concluded: “Our post marketing clinical study showed that Gene-Eden-VIR/Novirin is a safe and effective treatment against the Human Papillomavirus (HPV).” In fact the study showed that Gene-Eden-VIR decreased the duration, severity, and frequency of symptoms caused by the HPV virus.]

Do you want to help your immune system target the latent HPV virus? Take Gene-Eden-VIR/Novirin.

The development of Gene-Eden-VIR/Novirin was inspired by Dr. Hanan Polansky’s research of latent viruses. Before you buy Gene-Eden-VIR/Novirin, you might want to read about Dr. Hanan Polansky and his highly acclaimed scientific achievements. Just enter his name in Google, and follow the links.

Other less common HPV-related cancers, such as cancers of the vulva, vagina, anus and penis, also may not have signs or symptoms until they are advanced.

How do people get genital HPV infections?

Genital HPV is passed on through genital contact, most often during vaginal and anal sex. A person can have HPV even if years have passed since he or she had sex. Most infected persons do not realize they are infected or that they are passing the virus to a sex partner.

Very rarely, a pregnant woman with genital HPV can pass HPV to her baby during vaginal delivery. In these cases, the child may develop warts in the throat or voice box – a condition called recurrent respiratory papillomatosis (RRP).

How does HPV cause genital warts and cancer?

HPV can cause normal cells on infected skin or mucous membranes to turn abnormal. Most of the time, you cannot see or feel these cell changes. In most cases, the body fights off HPV naturally and the infected cells then go back to normal.

  • Sometimes, low-risk types of HPV can cause visible changes that take the form of genital warts.

  • If a high-risk HPV infection is not cleared by the immune system, it can linger for many years and turn abnormal cells into cancer over time. About 10% of women with high-risk HPV on their cervix will develop long-lasting HPV infections that put them at risk for cervical cancer. Similarly, when high-risk HPV lingers and infects the cells of the penis, anus, vulva, or vagina, it can cause cancer in those areas. But these cancers are much less common than cervical cancer.

[Again, Dr. Hanan Polansky describes in his book how the latent Human Papillomavirus (HPV) can cause cancer. Click on Simple Explanation of Dr. Polansky’s Discovery, to read more.]

How common are HPV and related diseases?

HPV infection. Approximately 20 million Americans are currently infected with HPV, and another 6.2 million people become newly infected each year. At least 50% of sexually active men and women acquire genital HPV infection at some point in their lives.

Genital warts. About 1% of sexually active adults in the U.S. have genital warts at any one time.

Cervical cancer. The American Cancer Society estimates that in 2008, 11,070 women will be diagnosed with cervical cancer in the U.S.

Other HPV-related cancers are much less common than cervical cancer. The American Cancer Society estimates that in 2008, there will be:

  • 3,460 women diagnosed with vulvar cancer;

  • 2,210 women diagnosed with vaginal and other female genital cancers;

  • 1,250 men diagnosed with penile and other male genital cancers; and

  • 3,050 women and 2,020 men diagnosed with anal cancer.

Certain populations may be at higher risk for HPV-related cancers, such as gay and bisexual men, and individuals with weak immune systems (including those who have HIV/AIDS). RRP is very rare. It is estimated that less than 2,000 children get RRP every year.

How can people prevent HPV?

A vaccine can now protect females from the four types of HPV that cause most cervical cancers and genital warts. The vaccine is recommended for 11 and 12 year-old girls. It is also recommended for girls and women age 13 through 26 who have not yet been vaccinated or completed the vaccine series.

For those who choose to be sexually active, condoms may lower the risk of HPV, if used all the time and the right way. Condoms may also lower the risk of developing HPV-related diseases, such as genital warts and cervical cancer. But HPV can infect areas that are not covered by a condom – so condoms may not fully protect against HPV. So the only sure way to prevent HPV is to avoid all sexual activity.

Individuals can also lower their chances of getting HPV by being in a mutually faithful relationship with someone who has had no or few sex partners. However, even people with only one lifetime sex partner can get HPV, if their partner was infected with HPV. For those who are not in long-term mutually monogamous relationships, limiting the number of sex partners and choosing a partner less likely to be infected may lower the risk of HPV. Partners less likely to be infected include those who have had no or few prior sex partners. But it may not be possible to determine if a partner who has been sexually active in the past is currently infected.

How can people prevent HPV-related diseases?

There are important steps girls and women can take to prevent cervical cancer. The HPV vaccine can protect against most cervical cancers (see above). Cervical cancer can also be prevented with routine cervical cancer screening and follow-up of abnormal results. The Pap test can identify abnormal or pre-cancerous changes in the cervix so that they can be removed before cancer develops. An HPV DNA test, which can find high-risk HPV on a woman’s cervix, may also be used with a Pap test in certain cases. The HPV test can help healthcare professionals decide if more tests or treatment are needed. Even women who got the vaccine when they were younger need regular cervical cancer screening because the vaccine does not protect against all cervical cancers.

There is currently no vaccine licensed to prevent HPV-related diseases in men. Studies are now being done to find out if the vaccine is also safe in men, and if it can protect them against HPV and related conditions. The FDA will consider licensing the vaccine for boys and men if there is proof that it is safe and effective for them. There is also no approved screening test to find early signs of penile or anal cancer. Some experts recommend yearly anal Pap tests for gay and bisexual men and for HIV-positive persons because anal cancer is more common in these populations. Scientists are still studying how best to screen for penile and anal cancers in those who may be at highest risk for those diseases.

Generally, cesarean delivery is not recommended for women with genital warts to prevent RRP in their babies. This is because it is unclear whether cesarean delivery actually prevents RRP in infants and children.

Is there a test for HPV?

The HPV test on the market is only used as part of cervical cancer screening. There is no general test for men or women to check one’s overall “HPV status. HPV usually goes away on its own, without causing health problems. So an HPV infection that is found today will most likely not be there a year or two from now. For this reason, there is no need to be tested just to find out if you have HPV now. However, you should get tested for signs of disease that HPV can cause, such as cervical cancer.

  • Genital warts are diagnosed by visual inspection. Some health care providers may use acetic acid, a vinegar solution, to help identify flat warts. But this is not a sensitive test so it may wrongly identify normal skin as a wart.

  • Cervical cell changes (early signs of cervical cancer) can be identified by routine Pap tests. The HPV test can identify high-risk HPV types on a woman’s cervix, which can cause cervical cell changes and cancer.

  • As noted above, there is currently no approved test to find HPV or related cancers in men. But HPV is very common and HPV-related cancers are very rare in men.

Is there a treatment for HPV or related diseases?

There is no treatment for the virus itself, but a healthy immune system can usually fight off HPV naturally.

There are treatments for the diseases that HPV can cause:

Visible genital warts can be removed by patient-applied medications, or by treatments performed by a health care provider. Some individuals choose to forego treatment to see if the warts will disappear on their own. No one treatment is better than another.

Cervical cancer is most treatable when it is diagnosed and treated early. There are new forms of surgery, radiation therapy, and chemotherapy available for patients [see www.cancer.org]. But women who get routine Pap testing and follow up as needed can identify problems before cancer develops. Prevention is always better than treatment.

Other HPV-related cancers are also more treatable when diagnosed and treated early. There are new forms of surgery, radiation therapy, and chemotherapy available for patients. [see www.cancer.org]

Where can I get more information?

Click on the following more personal questions for their answers.

  • Q: My doctor diagnosed me with HPV genital warts two days ago and it is eating me up. My initial reaction was that I had a virus and that usually means trouble. How did I get it? Could I have gotten HPV from kissing? Oral sex? Now I’m really worried! What are first outbreaks generally like? How long do they last and how often do they reoccur? I’ve looked up HPV online and have read a lot of conflicting information. 

    A: It’s true that on the internet you can find a variety of answers and you’re never quite sure who or what to believe. Most often, government or publicly funded websites have the most conclusive and accurate HPV information. That being said, the Australian Government Department of Health and Ageing states that: 

    “Genital HPV is spread through genital skin contact during sexual activity. As viruses are microscopic, HPV can pass through tiny breaks in the skin. HPV is not spread in blood or other body fluids. While condoms are an important barrier to many sexually transmitted infections, they offer limited protection against HPV as they do not cover all of the genital skin. 

    Because the virus can be hidden in a person’s cells for months or years, having a diagnosis of HPV does not necessarily mean that you, or your partner, have been unfaithful. For most people it is probably impossible to determine when and from whom HPV was contracted.” 

    Genital warts may appear or disappear at different times. Even if genital warts are just appearing now on your skin, your body may have been carrying the HPV virus for a long time. 

    For some people, only a few warts appear, while in others more severe viral reactions may occur. The Australian Government Department of Health and Ageing explains that “HPV is a very common virus, with four out of five people having it at some stage of their lives”. They also state that “Genital HPV is so common that it could be considered a normal part of being a sexually active person.” 

    Nonetheless, with genital wart removal treatment and strengthening your immune system against future viral infection, genital warts can disappear – but there is no guarantee that the genital warts won’t reappear.

    The HPV virus remains in your body forever. However, if you want to help your immune system fight the virus, then there are a number of alternatives such as general herbal remedies that strengthen the immune system, or more targeted natural dietary supplements, such as Gene-Eden-VIR, which can boost the immune system against the latent human papillomavirus (HPV). 

  • Q: What is a virus? Are viruses different from bacteria? 

    A: A human papilloma virus (HPV) is a member of the papilloma virus family of viruses that is capable of infecting humans. While the majority of the nearly 200 known types of HPV cause no symptoms in most people, some types can cause warts, while others can – in a minority of cases – lead to cancers of the cervix, vulva, vagina, and anus in women or cancers of the anus and penis in men. 

    More than 30 to 40 types of HPV are typically transmitted through sexual contact and infect the sexual organs. Some sexually transmitted HPV types may cause genital warts. 

    A virus is the smallest and most stripped down form of life. It includes only a set of genes, called viral DNA (or RNA), and a shell to protect these genes. Viruses don’t have proteins, or cells, only genes and a shell. Bacteria, on the other hand, are cellular organisms. Bacteria have cells. When a virus enters a human cell, the viral DNA enters the nucleus, where it starts to manufacture its proteins. Viruses are the ultimate parasites. They can’t replicate outside a living organism. Many regard viruses outside cells as inanimate objects, that is, non-living objects. In contrast, bacteria can live in any hospitable environment, such as water, soil, etc. Also, while we have a great weapon against bacteria called antibiotics, we have no such weapon against viruses. 

  • Q: I was diagnosed with HPV last month. My gynecologist said it was quite common but I’m worried. Can I have a regular sex life now without infecting my boyfriend? 

    A: If you choose to be sexually active, condoms may lower the risk of HPV. To be most effective, they should be used with every sex act, from start to finish. Condoms may also lower the risk of developing HPV-related diseases, such as genital warts and cervical cancer. However, HPV can infect areas that are not covered by a condom, such as the base of the penis – so condoms may not completely protect against HPV. 

    You can lower your chances of getting HPV by being in a faithful relationship with one partner and choosing a partner who has had no or few prior sex partners. But even people with only one lifetime sex partner can get HPV. In reality, it may not be possible to determine if a partner who has been sexually active in the past is currently infected. The only sure way to prevent HPV is to avoid all sexual activity. 

    We also propose that you and your partner take Gene-Eden-VIR. The VIR formula was designed to boost the immune system against the latent HPV virus that already resides in your body. It can also boost your partner’s immune system against the latent HPV.

  • Q: How is it related to cervical cancer? My gynecologist says I should have a Colposcopy exam to make sure the HPV virus I contracted is not cancerous. This sounds pretty scary. What are the risks to my health? 

    A: If HPV is left untreated, it may be harmful to your health – especially for women. According to the Australian Government Department of Health and Ageing: 

    “A few of the many types of HPV have been linked with causing abnormalities of the cervix and in some cases the development of cancer of the cervix. 

    … It is important to remember that most women who have HPV clear the virus naturally and do not go on to develop cervical cancer. 

    … In a small number of women, the HPV stays in the cells of the cervix. When the infection is not cleared, there is an increased risk of developing abnormalities. In very rare cases, these abnormalities of the cervix can progress to cancer. When cervical cancer develops, HPV is found in almost all cases. Having regular Pap smears is the best way to ensure that any changes are monitored and managed to protect your health. 

    … If you have early cell changes due to HPV, there is a strong likelihood that these changes will clear up naturally in 8 to 14 months. Because of this, and the fact that cancer of the cervix takes around 10 years to develop, your doctor may recommend simply having another Pap smear in 12 months time.” 

    If you want to help your immune system maintain a low concentration of the latent HPV virus, you might want to consider a dietary supplement such as Gene-Eden-VIR. 

  • Q: I’m 30 years old. I am three months pregnant. I remember that about 10 years ago I was diagnosed with HPV after a few warts appeared on my vulva. When the warts went away, I no longer worried about them. Now that I’m pregnant, I’m worried all over again, and this time about my unborn child. What are the health risks to my unborn child? 

    A: Thus far, no link has been found between HPV and miscarriage, premature delivery, or other pregnancy complications. 

    Women who have HPV during pregnancy may worry that the HPV virus may harm their unborn child. However, in most cases, the human papilloma virus does not affect the developing baby. Nor does HPV infection usually change the way a woman is cared for during pregnancy. It is important, however, that your obstetrician know about your HPV infection. 

    Due to the fact that you’re pregnant, a Pap test should be taken at the first prenatal visit. If it shows abnormalities, the doctor will order more tests. 

    Additional tests could include an HPV test. Cells are collected from the cervix and analyzed in the laboratory to detect the high-risk types of HPV associated with cancer. Your doctor may also decide to do a colposcopy, in which a lighted device is used to closely examine the cervix for abnormal tissue changes. 

    However, keep in mind that there are over 100 different types of HPV that may harm the body. There are also some that affect the genitals. Genital HPV is similar to the virus which causes warts on other parts of the body. 

  • Q: I recently noticed a few reddish bumps on the tip of my penis. Does anyone know if it’s HPV or..??? What treatments are available? 

    A: If you would like to see pictures of HPV warts to compare to your “reddish bumps,” type the keyword “HPV genital warts pictures” into Google Images. We also suggest that you consult with your doctor. He’ll probably run some tests and let you know what you have. Finally, you can become more knowledgeable by visiting online forums and other informative websites. A list of website links is available at the bottom of this page. 

    With genital wart removal treatment, genital warts can disappear almost immediately. However, the HPV virus remains in your body forever so strengthening your immune system against the human papilloma virus (HPV) should be your first priority. Gene-Eden-VIR, a natural dietary supplement, is especially designed to boosts the immune system against the latent HPV, and other latent viruses.

  • Q: I had genital warts last year and had them frozen off. Now I’m in a loving relationship. Should I let her know? 

    A: There is no reason for you to be ashamed or concerned about telling your partner about your genital wart history. It is quite common. According to the Center for Disease control and Prevention, “at least 50% of sexually active people will have genital HPV at some time in their lives”. 

    Also the Australian Government Department of Health and Ageing states that “because the virus can be hidden in a person’s cells for months or years, having a diagnosis of HPV does not necessarily mean that you or your partner has been unfaithful. For most people it is probably impossible to determine when and from whom HPV was contracted.” 

    We also propose that you and your parter take Gene-Eden-VIR. It was deigned to boost the immune system against the latent HPV virus that already resides in your body. It can also boost the immune system of your partner against the latent HPV virus.

  • Q: I just got a call from my doctor telling me I have HPV. My doctor says I need to strengthen my immune system by eating more fruits and vegetables, and HPV will go away on its own. Is that all? Are there any medications I should take? Home remedies? Herbal or antiviral supplements? How can I build up my immunity to better fight off genital warts? 

    A: There are different ways to boost your immune system. Most experts will agree that more exercise, fresh fruits and vegetables, adequate sleep and refraining from nicotine and alcohol will help your body combat viruses. Added to that, you can learn more about herbal remedies, antiviral supplements and homeopathic solutions to see if they suit you. 

    You may also consider trying Gene-Eden-VIR, an natural dietary supplement designed to strengthen your system’s immunity against latent viruses. 

  • Q: My boyfriend and I both have HPV. We don’t know who gave it to whom, and we don’t really care. However, we still want to get rid of them somehow. Our doctor told us we have to be abstinent for at least 2 years. Isn’t there anything else we could do? 

    A: Your doctor was giving you the most full-proof advice. First of all, you should find out what kind of HPV you have and how serious your case is, as compared to your boyfriend. Even though you both have HPV your boyfriend should still use a condom. Also, depending on the HPV strain you may be able to get vaccinated or, in the case of genital warts, reduce their frequency. 

    Also keep in mind that genital warts can be removed surgically, with chemical treatment, or with painless electric current – but HPV remains in your system forever. That being said, there are natural ways of dealing with genital warts and HPV. By strengthening your immune system, you can assist your body in fighting HPV. Gene-Eden-VIR is a natural dietary supplement that can boost the immune system against the latent human papilloma virus (HPV).

  • Q: I just got my genital warts removed from my penis by freezing. Does that mean as soon as my warts clear that I am cured? I am not stuck with this virus forever, right?? I have a new girl friend and I’d like to know if it’s important to tell her. My doctor says after 6 months without warts I can say I am cured. But I heard that for some people the warts never go way. Is this true? How do I know if I’m cured? 

    A: You may have read a variety of answers through internet or other research. It’s true that once your immune system strengthens and you’ve removed the genital warts, you can feel confident that the warts won’t reappear. 

    Here is what the Australian Government Department of Health and Ageing has to offer: 

    “There is no cure or treatment for HPV. It will, in most cases, be cleared up by your immune system. Consult your doctor or health practitioner if you are concerned about genital warts because of their appearance, or if they are causing you discomfort. There are a range of treatment options for warts.” 

    You might simply ask yourself, would I want to know if my partner has or has had any sexually transmitted diseases? Naturally, the answer is yes. Therefore, it’s advisable to be honest and open with him. There’s nothing to be ashamed of, HPV is quite common and treatment is readily available.

  • A: There is a good deal of information regarding HPV testing and why it’s ordered. 

    The following is from the American Association for Clinical Chemistry at www.labtestsonline.org: 

    “Traditionally, genital HPV infection has been detected as abnormal cell changes on a Pap smear, a test used primarily to detect cancer of the cervix (the lower part of the uterus or womb) or conditions that may lead to cancer. During a Pap smear, cervical cells are evaluated under a microscope. “Low-grade” changes to the cells on a Pap smear may indicate an HPV infection. 

    DNA testing for HPV has gained widespread acceptance as an additional cervical cancer screening tool and as follow-up to abnormal changes detected with a Pap smear. There are now several such DNA HPV tests, some of which have been approved for marketing by the FDA, that can detect either the majority of the high-risk types of HPV or specific subtypes, such as HPV-16 and HPV-18.” 

    The American Cancer Society recommends that women over the age of 18 and all sexually active women have a Pap smear yearly to screen for cancer or situations that may develop into cancer. In women over 21, when results indicate abnormal changes that may be due to a high-risk type of HPV, then DNA HPV testing may be ordered as a follow-up test.” 

    The American College of Obstetricians and Gynecologists (ACOG) released guidelines in August 2003 recommending that women 30 years or older be offered an HPV DNA test in addition to their Pap smear and pelvic exam. If the HPV DNA test and Pap smear are negative and the woman does not have an underlying health condition, such as HIV or immunosuppression, then the guidelines suggest that she may wait three years before having another Pap smear and HPV DNA test. Patients who are positive for high-risk HPV, have abnormal cell changes on their Pap smear, or have underlying medical conditions should be screened more frequently, with the frequency to be determined by the patient and her doctor on an individual basis.” 

    Some doctors will test men who fall into a high-risk category. Men who have sex with men and those who have HIV may be tested for HPV. Evaluating the risk of HPV-related diseases of the anal canal in men is becoming more common.” 

    For the most up-to-date HPV testing information consult your physician or gynecologist. 

  • A: Here is useful information regarding vaccination from the Centers for Disease Control and Prevention (CDC): “HPV vaccines (“shots”) are available for males and females to protect against the types of HPV that most commonly cause health problems.” 

    … Two vaccines (Cervarix and Gardasil) are available to protect females against the types of HPV that cause most cervical cancers. One of these vaccines (Gardasil) also protects against most genital warts. Both vaccines are recommended for 11 and 12 year-old girls, and for females 13 through 26 years old, who did not get any or all of the three recommended doses when they were younger. These vaccines can also be given to girls beginning at age 9. It is recommended that females get the same vaccine brand for all three doses, whenever possible.” 

    … One available vaccine (Gardasil) protects males against most genital warts. This vaccine is available for boys and men, 9 through 26 years of age.” 

    … The best way a person can be sure to get the most benefit from HPV vaccination is to complete all three doses before beginning sexual activity.”

  • A: Actually, not necessarily. 

    The end point of all the efficacy studies for Gardasil was not the prevention of cancer. Researchers couldn’t actually assess the development of cervical cancer following the vaccine because this process normally takes 20 to 40 years and their studies stopped after just five. 

    Instead, Merck’s scientists decided that the presence of atypical cervical cells was a valid “surrogate end point,” or substitute for cancer. They used this hypothesis despite the fact that there is no evidence that the types of cervical lesions they chose as their end point would eventually lead to cancer. [1] 

    Merck has never acknowledged that their entire premise for the efficacy of Gardasil rests on pure speculation. In fact, many if not most atypical cervical cells resolve on their own without intervention. [2] 


    [1] Rothman SM and Rothman DJ, Marketing HPV Vaccine: Implications for Adolescent Health and Medical Professionalism, JAMA 2009, 302(7); 781-786. 

    [2] Tomljenovic L and Shaw CA, Human Papillomavirus (HPV) Vaccine Policy and Evidence-Based Medicine: Are They at Odds? Annals of Medicine December 22, 2011, http://informahealthcare.com/doi/abs/10.3109/07853890.2011.645353

  • A: Not at all. 

    Gardasil is designed to prevent only 4 HPV strains: 16 and 18, which can cause cervical cancer, and 6 and 11, which can cause genital warts. However, there are 150 other types of HPVs, at least 15 of which can cause cancer, and Gardasil provides no protection against these other strains. [1][2] 

    Gardasil’s protection is incredibly limited. 


    [1] Human Papillomaviruses and Cancer, National Cancer Institute, September 7, 2011, http://www.cancer.gov/cancertopics/factsheet/Risk/HPV/print 

    [2] Haug CJ, Human Papillomavirus Vaccination – Reasons for Caution, New England Journal of Medicine, August 21, 2008 

  • A: There’s not enough evidence. Merck’s study of HPV vaccine efficacy in males published in the New England Journal of Medicine states that Gardasil is 89% effective against genital warts and 75% effective against anal cancer. 

    Given the fact that there are approximately 300 annual deaths from of anal/rectal cancer among men in the United States, one wonders how Merck was able to prove such a huge reduction in such a rare problem. 

    As with the female group, external lesions substituted for actual cancer with no proof that lesions of that type actually lead to cancer at all. Yet, Merck’s statistics regarding their cancer substitute penile/perianal/perineal intraepithelial neoplasia (PIN) listed in their appendix to the article show that in men who did not have HPV prior to vaccination, both the vaccinated group and the placebo group had the same number of these types of lesions, making the observed efficacy of Gardasil minus 98%! 

    And for HPV strain 18-related genital lesions, there were actually more lesions in the vaccinated group than the placebo group. So as in the previous study, Merck’s impressive numbers for the efficacy of Gardasil in men can only be attained by excluding one-quarter of the study participants. When everyone is included and all outcomes are assessed, the efficacy drops to zero! [1] 


    [1] Lenzer J, Should Boys be Given the HPV Vaccine? The Science is Weaker than the Marketing, Discover Magazine, November 14, 2011

You can also find more information by clicking on the following links.

Sexually Transmitted Diseases
Human Papillomavirus (HPV) Infection
HPV Vaccination
Cervical Cancer

Order Publications Online

CDC-INFO Contact Center
1-800-CDC-INFO (1-800-232-4636)
Email: cdcinfo@cdc.gov

CDC National Prevention Information Network (NPIN)  
P.O. Box 6003
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ASHA – National HPV and Cervical Cancer Prevention Resource Center

American Cancer Society (ACS)


American Cancer Society. Cancer Facts & Figures, 2008. Atlanta: American Cancer Society: 2008.
Centers for Disease Control and Prevention. Sexually Transmitted Diseases Treatment Guidelines 2006. MMWR 2006; 55 [No. RR-11].

Dunne EF, Unger ER, Sternberg M, McQuillan G, Swan DC, Patel SS, Markowitz LE. Prevalence of HPV infection among females in the United States. JAMA. 2007;297(8):813-9.

FUTURE II Study Group. Prophylactic efficacy of a quadrivalent human papillomavirus (HPV) vaccine in women with virological evidence of HPV infection J Infect Dis. 2007; 196:1438-1446.

FUTURE II Study Group. Quadrivalent vaccine against human papillomavirus to prevent high-grade cervical lesions. N Engl J Med. 2007; 356(19):1915-27.

Garland SM, Hernandez-Avila M, Wheeler CM, Perez G, Harper DM, Leodolter S, et al.  Females United to Unilaterally Reduce Endo/Ectocervical Disease (FUTURE) I Investigators. Quadrivalent vaccine against human papillomavirus to prevent anogenital diseases. N Engl J Med. 2007; 356(19):1928-43.

Koutsky LA, Kiviat NB. Genital human papillomavirus. In: K. Holmes, P. Sparling, P. Mardh et al (eds). Sexually Transmitted Diseases, 3rd edition. New York: McGraw-Hill, 1999, p. 347-359.

Kiviat NB, Koutsky LA, Paavonen J. Cervical neoplasia and other STD-related genital tract neoplasias. In: K. Holmes,  P. Sparling, P. Mardh et al (eds). Sexually Transmitted Diseases, 3rd edition. New York: McGraw-Hill, 1999, p. 811-831.

Markowitz LE, Dunne EF, Saraiya M, Lawson HW, Chesson H, Unger ER. Quadrivalent human papillomavirus vaccine: Recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR. 2007; 56: 1-24.

Myers ER, McCrory DC, Nanda K, Bastian L, Matchar DB. Mathematical model for the natural history of human papillomavirus infection and cervical carcinogenesis. American Journal of Epidemiology 2000; 151(12):1158-1171.

Paavonen J, Jenkins D, Bosch FX, Naud P, Salmeron J, Wheeler CM et al. Efficacy of a prophylactic adjuvanted bivalent L1 virus-like-particle vaccine against infection with human papillomavirus types 16 and 18 in young women: an interim analysis of a phase III double-blind, randomised controlled trial. Lancet 2007;370(9596):1414.

Weinstock H, Berman S, Cates W.  Sexually transmitted disease among American youth: Incidence and prevalence estimates, 2000.  Perspectives on Sexual and Reproductive Health 2004; 36: 6-10.

Winer R, Hughes JP, Feng Q, et al. Consistent condom use from time of first vaginal intercourse and the risk of genital human papillomavirus infection in young women. N Engl J Med. 2006;354:2645-2654.